Difference between revisions of "Analog Genetic Circuits (Microbes as Machines)"
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[[File:repressilator_plasmids.png|400px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]] | [[File:repressilator_plasmids.png|400px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]] | ||
− | ==== [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.pdf| | + | ==== Download Pre-Discussion Questions [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.pdf|(PDF)]] [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.doc|(DOC)] ==== |
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Revision as of 21:29, 16 February 2015
Contents |
Download Pre-Discussion Questions (PDF) [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.doc|(DOC)]
Such 'rational network design' may lead both to the engineering of new cellular behaviours and to an improved understanding of naturally occurring networks [2].
Required Reading/Viewing
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- Error fetching PMID 10659856:
Describes the artificial "repressilator" circuit. Also, view the movie of it in action. - Error fetching PMID 10659857:
Describes an artificial "toggle switch" circuit. - Explanation of the toggle switch and repressilator by J. Chris Anderson (YouTube)
Assigned Papers
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- Error fetching PMID 19478183:
Bacteria that can count to three. - Error fetching PMID 22178928:
Synchronization and modulation of oscillations across multiple cell populations.
Additional Resources
- Repressilator in TinkerCell (YouTube)
Movie shows how to create and model the repressilator in TinkerCell