Difference between revisions of "Analog Genetic Circuits (Microbes as Machines)"

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(Additional Resources)
(Required Reading/Viewing)
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<biblio>
 
<biblio>
 
#Elowitz2000 pmid=10659856
 
#Elowitz2000 pmid=10659856
// Describes the artificial "repressilator" circuit.
+
// Describes the artificial "repressilator" circuit. Also, view the [http://www.elowitz.caltech.edu/publications/brepressilator-01-bwfluor.avi movie] of it in action.
 
#Gardner2000 pmid=10659857
 
#Gardner2000 pmid=10659857
 
// Describes an artificial "toggle switch" circuit.
 
// Describes an artificial "toggle switch" circuit.

Revision as of 06:10, 16 February 2015

Repressilator [1]. Image from Wikipedia article.

Contents

Download Pre-Discussion Questions (PDF)

Such 'rational network design' may lead both to the engineering of new cellular behaviours and to an improved understanding of naturally occurring networks [2].

Required Reading/Viewing

Error fetching PMID 10659856:
Error fetching PMID 10659857:
  1. Error fetching PMID 10659856: [Elowitz2000]
    Describes the artificial "repressilator" circuit. Also, view the movie of it in action.
  2. Error fetching PMID 10659857: [Gardner2000]
    Describes an artificial "toggle switch" circuit.
  3. Overview of the Toggle Switch and Repressilator (YouTube) [Anderson2014]
All Medline abstracts: PubMed | HubMed

Assigned Papers

Error fetching PMID 19478183:
Error fetching PMID 22178928:
  1. Error fetching PMID 19478183: [Friedland2009]
    Bacteria that can count to three.
  2. Error fetching PMID 22178928: [Prindle2012]
    Synchronization and modulation of oscillations across multiple cell populations.
All Medline abstracts: PubMed | HubMed

Additional Resources

  1. Repressilator in TinkerCell (YouTube) [Chandran2011]
    Movie shows how to create and model the repressilator in TinkerCell