Biocontainment (Microbes as Machines)

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How mutations in biocontainment mechanisms can lead to the survival of escape mutants [1].

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...if speculations correctly predict the future use of synthetic biology, the technology will scale to large industrial volumes, introduce large numbers of synthetic organisms into the environment for bioremediation, and be used in private spaces where dispersal and disposal are difficult to monitor [1].

Required Reading/Viewing

Error fetching PMID 23355834:
  1. Error fetching PMID 23355834: [Moe-Behrens2013]
    Reviews the development of biocontainment technologies for organisms and recombinant genes

Assigned Papers

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  1. Error fetching PMID 24805238: [Malyshev2014]
    Using a nonnatural base in DNA replicated in a living organism
  2. Error fetching PMID 24847673: [Wright2015]
    Creation of a plasmid that prevents recombinant genes from being transferred to other organisms
  3. Error fetching PMID 25567985: [Gallagher2015]
    Tests of multiple biocontainment strategies for organisms
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