Difference between revisions of "Expanding the Genetic Code (Microbes as Machines)"

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[[File:ODonoghue2013_Genetic_Code_Expansion.png|thumb|350px|right|Example of genetic parts needed to reassign a codon to an unnatural amino acid<cite>ODonoghue2013</cite>.]]
 
[[File:ODonoghue2013_Genetic_Code_Expansion.png|thumb|350px|right|Example of genetic parts needed to reassign a codon to an unnatural amino acid<cite>ODonoghue2013</cite>.]]
  

Revision as of 03:02, 13 April 2015

Example of genetic parts needed to reassign a codon to an unnatural amino acid[1].

Download Pre-Discussion Questions (PDF)

The genetic code was thought to be immutable...Recent developments demonstrate not only that the genetic code can evolve but also that rewiring translation to genetically encode more (possibly many more) than 20 amino acids, primarily by recoding UAG, is both feasible and desirable.[1]

Required Reading/Viewing

Error fetching PMID 24045798:
  1. Error fetching PMID 24045798: [ODonoghue2013]
    Overview of topic

Assigned Papers

Error fetching PMID 20154731:
Error fetching PMID 24136966:
  1. Error fetching PMID 20154731: [Neumann2010]
    Quadruplet codons
  2. Error fetching PMID 24136966: [Lajoie2013]
    "Amberless" E. coli
All Medline abstracts: PubMed | HubMed

Additional Resources

Error fetching PMID 20307192:
  1. Error fetching PMID 20307192: [Liu2010]
    Exhaustive review of the topic