Difference between revisions of "Gene Therapy (Biotechnology and Society)"

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(Required Reading/Viewing)
(Required Reading/Viewing)
 
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==== [[Media:Gene_Therapy_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
 
==== [[Media:Gene_Therapy_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
  
[[File:empty.jpg|450px|thumb|right|Caption]]]  
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[[File:AAV_Gene_Therapy.jpg|400px|thumb|right|Glybera ([http://en.wikipedia.org/wiki/Alipogene_tiparvovec Alipogene tiparvovec]) gene therapy]]
  
 
== Required Reading/Viewing ==
 
== Required Reading/Viewing ==
 +
 +
We will discuss gene therapy for two diseases: SCID (Severe Combined Immunodeficiency Disease) and Familial Lipoprotein Lipase Deficiency (LPLD).
  
 
<biblio>
 
<biblio>
# [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah.
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# Carl Zimmer. Gene Therapy emerges from disgrace to be the next big thing, again. Wired Science Blogs. August 13, 2013.
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// Read article at [http://www.wired.com/wiredscience/geneticfuture/ wired.com].
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#Bandage2013 [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah.
 
// Especially, check out the "Tools of the Trade" and "Space Doctor" links.
 
// Especially, check out the "Tools of the Trade" and "Space Doctor" links.
 
#Hacein2008 pmid=18688285
 
#Hacein2008 pmid=18688285
// Study characterizing genomes SCID patients who developed Leukemia after successful gene therapy.
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// Study characterizing the genomes of SCID patients who developed Leukemia after successful gene therapy. Feel free to skim for key details.
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#Bryant2013 pmid=23808604
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// Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014).
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#Giacca2010 isbn=8847016428
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// [http://link.springer.com/chapter/10.1007/978-88-470-1643-9_5 Read Chapter 5: Ethical and Social Problems of Gene Therapy]
 
</biblio>
 
</biblio>
  
 
== Additional Resources ==
 
== Additional Resources ==
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 +
<biblio>
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#Griesenbach2011 pmid=21443272
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// Review of developments in gene therapy for cystic fibrosis over the last ~20 years.
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#Glybera [http://www.uniqure.com/products/glybera/ Glybera] - commercial gene therapy product available in Europe.
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</biblio>

Latest revision as of 19:29, 28 October 2013

Download Pre-Discussion Questions (PDF)

Glybera (Alipogene tiparvovec) gene therapy

Required Reading/Viewing

We will discuss gene therapy for two diseases: SCID (Severe Combined Immunodeficiency Disease) and Familial Lipoprotein Lipase Deficiency (LPLD).

Error fetching PMID 18688285:
Error fetching PMID 23808604:
  1. Zimmer. Gene Therapy emerges from disgrace to be the next big thing, again. Wired Science Blogs. August 13, 2013. [Carl]
    Read article at wired.com.
  2. Gene Therapy: Molecular Bandage? Educational website at the University of Utah. [Bandage2013]
    Especially, check out the "Tools of the Trade" and "Space Doctor" links.
  3. Error fetching PMID 18688285: [Hacein2008]
    Study characterizing the genomes of SCID patients who developed Leukemia after successful gene therapy. Feel free to skim for key details.
  4. Error fetching PMID 23808604: [Bryant2013]
    Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014).
  5. ISBN:8847016428 [Giacca2010]
    Read Chapter 5: Ethical and Social Problems of Gene Therapy
All Medline abstracts: PubMed | HubMed

Additional Resources

Error fetching PMID 21443272:
  1. Error fetching PMID 21443272: [Griesenbach2011]
    Review of developments in gene therapy for cystic fibrosis over the last ~20 years.
  2. Glybera - commercial gene therapy product available in Europe. [Glybera]