Gene Therapy (Biotechnology and Society)

Gene Therapy (Biotechnology and Society)

Download Pre-Discussion Questions (PDF)

Glybera (Alipogene tiparvovec) gene therapy

Required Reading/Viewing

We will discuss gene therapy for two diseases: SCID (Severe Combined Immunodeficiency Disease) and Familial Lipoprotein Lipase Deficiency (LPLD).

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1. Zimmer. Gene Therapy emerges from disgrace to be the next big thing, again. Wired Science Blogs. August 13, 2013.

   Read article at wired.com.

2. Gene Therapy: Molecular Bandage? Educational website at the University of Utah.

   Especially, check out the "Tools of the Trade" and "Space Doctor" links.

3. Study characterizing the genomes of SCID patients who developed Leukemia after successful gene therapy. Feel free to skim for key details.

4. Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014).

5. ISBN:8847016428

   Read Chapter 5: Ethical and Social Problems of Gene Therapy

Additional Resources

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6. Review of developments in gene therapy for cystic fibrosis over the last ~20 years.

7. Glybera - commercial gene therapy product available in Europe.