Difference between revisions of "Gene Therapy versus Human Genome Editing (Biotechnology and Society 2016)"
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== Required Reading/Viewing == | == Required Reading/Viewing == | ||
| − | * [http://www.wired.com/wiredscience/geneticfuture/ | + | * [http://www.wired.com/wiredscience/geneticfuture/ Gene Therapy emerges from disgrace to be the next big thing, again.] Carl Zimmer ''Wired Science Blogs'' August 13, 2013. |
* [https://www.technologyreview.com/s/535661/engineering-the-perfect-baby/ Engineering the Perfect Baby] Antonio Regalado ''MIT Technology Review'' March 5, 2015. <br>Use of CRISPR to | * [https://www.technologyreview.com/s/535661/engineering-the-perfect-baby/ Engineering the Perfect Baby] Antonio Regalado ''MIT Technology Review'' March 5, 2015. <br>Use of CRISPR to | ||
* [http://www.sciencemag.org/news/2016/06/scientists-reveal-proposal-build-human-genome-scratch Scientists reveal proposal to build human genome from scratch] Kelly Servick ''Science'' June 2, 2016. <br>Short article describing the Human Genome Project–Write meeting. | * [http://www.sciencemag.org/news/2016/06/scientists-reveal-proposal-build-human-genome-scratch Scientists reveal proposal to build human genome from scratch] Kelly Servick ''Science'' June 2, 2016. <br>Short article describing the Human Genome Project–Write meeting. | ||
==== Additional Resources ==== | ==== Additional Resources ==== | ||
| − | * [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah. | + | * [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah. <br>Especially, check out the "Tools of the Trade" and "Space Doctor" links. |
| − | <br>Especially, check out the "Tools of the Trade" and "Space Doctor" links. | + | |
* [http://link.springer.com/chapter/10.1007/978-88-470-1643-9_5 Read Chapter 5: Ethical and Social Problems of Gene Therapy]<br>Access from on-campus to read. | * [http://link.springer.com/chapter/10.1007/978-88-470-1643-9_5 Read Chapter 5: Ethical and Social Problems of Gene Therapy]<br>Access from on-campus to read. | ||
Revision as of 13:26, 30 October 2016
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Everyone: SCID
Required Reading/Viewing
- Gene Therapy emerges from disgrace to be the next big thing, again. Carl Zimmer Wired Science Blogs August 13, 2013.
- Engineering the Perfect Baby Antonio Regalado MIT Technology Review March 5, 2015.
Use of CRISPR to - Scientists reveal proposal to build human genome from scratch Kelly Servick Science June 2, 2016.
Short article describing the Human Genome Project–Write meeting.
Additional Resources
- Gene Therapy: Molecular Bandage? Educational website at the University of Utah.
Especially, check out the "Tools of the Trade" and "Space Doctor" links. - Read Chapter 5: Ethical and Social Problems of Gene Therapy
Access from on-campus to read.
Familial Lipoprotein Lipase Deficiency (LPLD) Czar
Required Reading/Viewing
- Bryant, L.M., Christopher, D.M., Giles, A.R., Hinderer, C., Rodriguez, J.L., Smith, J.B., Traxler, E.A., Tycko, J., Wojno, A.P., and Wilson, J.M. (2013). Lessons learned from the clinical development and market authorization of Glybera. Hum. Gene Ther. Clin. Dev. 24:55–64.
Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014). - Glybera Glybera - commercial gene therapy product available in Europe.
Error fetching PMID 21443272:
- Error fetching PMID 21443272:
Review of developments in gene therapy for cystic fibrosis over the last ~20 years.
SCID (Severe Combined Immunodeficiency Disease) Czar
Required Reading/Viewing
- Hacein-Bey-Abina, S., Garrigue, A., Wang, G.P., Soulier, J., Lim, A., Morillon, E., Clappier, E., Caccavelli, L., Delabesse, E., Beldjord, K., et al. (2008). Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J. Clin. Invest. 118:3132–3142.
