Talk:CH391L/S14/Oscillation

Talk:CH391L/S14/Oscillation

Comments

--drewtack (talk) 14:35, 24 March 2014 (CDT)Just starting with the introduction. I'm not entirely sure that you're introduction is appropriate for the subject matter; you should probably focus on biological or synthetic biology oscillations immediately.

• --Dennis Mishler (talk) 11:57, 25 March 2014 (CDT) Related to Drew's comment, Ashley I would like to see an actual introduction. What are oscillators? What is oscillations? I think you can then go into the descriptions that you already included.

• --Dennis Mishler (talk) 12:04, 25 March 2014 (CDT) I've never heard of this before... Is this a typo?: "Entertainment is defined as the systematic process of synchronization of the biological network."

• --Dennis Mishler (talk) 12:04, 25 March 2014 (CDT) In Biochemical Oscillations, you introduce A LOT of big words/concepts. “negative feedback, time delay, sufficient ‘nonlinearity’ of the reaction kinetics and proper balancing of the timescales of opposing chemical reactions.” Are you going to refer to these in the future, or give examples, or somehow relate back to these terms later?

• --Dennis Mishler (talk) 12:09, 25 March 2014 (CDT) Grammar in the last sentence (maybe a typo) of the repressilator section needs to be fixed.

• --Alejandro Gutierrez (talk) 06:25, 28 March 2014 (CDT) For the future directions section, is it possible to add an example of how the oscillators may be used, in a complex circuit or otherwise? I know it is sometimes difficult to find literature on the more complex theoretical circuits, but if you could find one or two examples, it would help my understanding of the subject.

• --Liz (talk) 07:22, 28 March 2014 (CDT) Agree with above statements about introduction- it seems colloquial and disjointed. Better transitions would help tie the ideas together. Also I think it would be really helpful here to have an figure illustrating the idea of an oscillator and how it functions/can be described- can you find something like that in a review? Why does the "entertainment" belong in this section? I'm not getting much from the biochemical oscillator section. Like we discussed in class, it would help to relate the terms of the equation to real life variables, or if you can't do that exactly at least make some explanation of why it was found to be a valid equation. Some more detail about the behavior of the biochemical oscillators you mention would be helpful- even going into detail (ie explaining how one fits the parameters you mention at top) for one and listing the others would be an improvement. Agree with Dennis that the wording of your Repressilator section could be cleaned up and clarified. I would resize your figure if possible to match the width of the article. As far as captions go, I would say list them as citations and just have the number at the end of your caption, not the whole link right in there.