Difference between revisions of "Wolbachia versus Gene Drives for Mosquito Control (Biotechnology and Society 2016)"
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==== [[Media:Policy_Czar_Template.docx | Download Policy Czar Template (MS Word)]] ==== | ==== [[Media:Policy_Czar_Template.docx | Download Policy Czar Template (MS Word)]] ==== | ||
− | == Everyone: Overview == | + | == Everyone: Overview of Wolbachia and CRISPR Gene Drives == |
==== Required Reading/Viewing ==== | ==== Required Reading/Viewing ==== | ||
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* [http://www.bloomberg.com/news/articles/2016-06-16/gates-says-altered-mosquitoes-are-next-weapon-in-malaria-fight Mosquito Is Next Weapon to Fight Malaria] Caroline Chen ''Bloomberg News'' June 16, 2016.<br>Watch the 4 minute video at the top of the page. | * [http://www.bloomberg.com/news/articles/2016-06-16/gates-says-altered-mosquitoes-are-next-weapon-in-malaria-fight Mosquito Is Next Weapon to Fight Malaria] Caroline Chen ''Bloomberg News'' June 16, 2016.<br>Watch the 4 minute video at the top of the page. | ||
* [https://www.sciencenews.org/article/gene-drives-spread-their-wings Gene drives spread their wings] Tina Saey ''Science News'' Dec 2, 1025. | * [https://www.sciencenews.org/article/gene-drives-spread-their-wings Gene drives spread their wings] Tina Saey ''Science News'' Dec 2, 1025. | ||
− | * [ | + | * [https://www.wired.com/2016/08/california-city-fending-off-zika-releasing-40000-mosquitoes-every-week/ A California City Is Fending Off Zika by Releasing 40,000 Mosquitoes Every Week] Sarah Zhang ''Wired'' Aug. 4, 2016. |
==== Additional Resources ==== | ==== Additional Resources ==== | ||
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==== Required Reading/Viewing ==== | ==== Required Reading/Viewing ==== | ||
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* [http://www.nature.com/news/us-reviews-plan-to-infect-mosquitoes-with-bacteria-to-stop-disease-1.19967 US reviews plan to infect mosquitoes with bacteria to stop disease] Emily Waltz ''Nature News'' May 24, 2016. | * [http://www.nature.com/news/us-reviews-plan-to-infect-mosquitoes-with-bacteria-to-stop-disease-1.19967 US reviews plan to infect mosquitoes with bacteria to stop disease] Emily Waltz ''Nature News'' May 24, 2016. | ||
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* [https://www.scientificamerican.com/article/how-a-tiny-bacterium-called-wolbachia-could-defeat-dengue/ How a Tiny Bacterium Called Wolbachia Could Defeat Dengue] Scott O'Neill ''Scientific American'' June 1, 2015. | * [https://www.scientificamerican.com/article/how-a-tiny-bacterium-called-wolbachia-could-defeat-dengue/ How a Tiny Bacterium Called Wolbachia Could Defeat Dengue] Scott O'Neill ''Scientific American'' June 1, 2015. | ||
* Frentiu F.D., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/24587459 Limited Dengue Virus Replication in Field-Collected ''Aedes aegypti'' Mosquitoes Infected with ''Wolbachia'']. ''PLoS Negl. Trop. Dis.'' '''8''':1–10. | * Frentiu F.D., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/24587459 Limited Dengue Virus Replication in Field-Collected ''Aedes aegypti'' Mosquitoes Infected with ''Wolbachia'']. ''PLoS Negl. Trop. Dis.'' '''8''':1–10. | ||
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== Medea Gene Drive Czar == | == Medea Gene Drive Czar == | ||
+ | ==== Required Reading/Viewing ==== | ||
* Akbari, OS., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/23654248 Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression]. ''ACS Synthetic Biology'' '''3''':915–928. | * Akbari, OS., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/23654248 Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression]. ''ACS Synthetic Biology'' '''3''':915–928. | ||
* Akbari OS, et al. (2013) [https://www.ncbi.nlm.nih.gov/pubmed/23541732 A synthetic gene drive system for local, reversible modification and suppression of insect populations]. ''Curr Biol.'' '''23''':671-677. | * Akbari OS, et al. (2013) [https://www.ncbi.nlm.nih.gov/pubmed/23541732 A synthetic gene drive system for local, reversible modification and suppression of insect populations]. ''Curr Biol.'' '''23''':671-677. | ||
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==== Additional Resources ==== | ==== Additional Resources ==== | ||
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* Champer J, Buchman A, Akbari OS. (2016) [https://www.ncbi.nlm.nih.gov/pubmed/26875679 Cheating evolution: engineering gene drives to manipulate the fate of wild populations]. ''Nat. Rev. Genet.'' '''17''':146–159. | * Champer J, Buchman A, Akbari OS. (2016) [https://www.ncbi.nlm.nih.gov/pubmed/26875679 Cheating evolution: engineering gene drives to manipulate the fate of wild populations]. ''Nat. Rev. Genet.'' '''17''':146–159. | ||
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==== Required Reading/Viewing ==== | ==== Required Reading/Viewing ==== | ||
+ | * [http://nas-sites.org/gene-drives/ Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values] ''The National Academy of Sciences Report''<br>Look at the "4 Page report in Brief" and the other links. | ||
* Oye K.A., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/25035410 Biotechnology. Regulating gene drives.] ''Science'' '''345''':626–628. | * Oye K.A., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/25035410 Biotechnology. Regulating gene drives.] ''Science'' '''345''':626–628. | ||
* Esvelt K.M., et al. [https://www.ncbi.nlm.nih.gov/pubmed/25035423 Concerning RNA-guided gene drives for the alteration of wild populations]. '''Elife''' ''3'':e03401. | * Esvelt K.M., et al. [https://www.ncbi.nlm.nih.gov/pubmed/25035423 Concerning RNA-guided gene drives for the alteration of wild populations]. '''Elife''' ''3'':e03401. |
Revision as of 15:53, 7 November 2016
Download Pre-Discussion Questions (MS Word)
Download Policy Czar Template (MS Word)
Everyone: Overview of Wolbachia and CRISPR Gene Drives
Required Reading/Viewing
- How Mosquitoes Use Six Needles to Suck Your Blood Deep Look via YouTube. Jun 7, 2016.
- Video of Bill Gates Releasing Mosquitoes Into Audience TED Talk excerpt on YouTube. Jul 8, 2009.
- Mosquito Is Next Weapon to Fight Malaria Caroline Chen Bloomberg News June 16, 2016.
Watch the 4 minute video at the top of the page. - Gene drives spread their wings Tina Saey Science News Dec 2, 1025.
- A California City Is Fending Off Zika by Releasing 40,000 Mosquitoes Every Week Sarah Zhang Wired Aug. 4, 2016.
Additional Resources
- Burt A. (2003) Site-specific selfish genes as tools for the control and genetic engineering of natural populations. Proc. Biol. Sci. 270:921–928.
Early paper discussing general concept and issues of gene drives.
Wolbachia Czar
Required Reading/Viewing
- US reviews plan to infect mosquitoes with bacteria to stop disease Emily Waltz Nature News May 24, 2016.
- How a Tiny Bacterium Called Wolbachia Could Defeat Dengue Scott O'Neill Scientific American June 1, 2015.
- Frentiu F.D., et al. (2014) Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia. PLoS Negl. Trop. Dis. 8:1–10.
Medea Gene Drive Czar
Required Reading/Viewing
- Akbari, OS., et al. (2014) Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. ACS Synthetic Biology 3:915–928.
- Akbari OS, et al. (2013) A synthetic gene drive system for local, reversible modification and suppression of insect populations. Curr Biol. 23:671-677.
- Wimmer EA. (2013) Comment: Insect biotechnology: controllable replacement of disease vectors. Curr Biol. 23:R453-R456.
Additional Resources
- Champer J, Buchman A, Akbari OS. (2016) Cheating evolution: engineering gene drives to manipulate the fate of wild populations. Nat. Rev. Genet. 17:146–159.
Gene Drive Ethics Czar
Required Reading/Viewing
- Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values The National Academy of Sciences Report
Look at the "4 Page report in Brief" and the other links. - Oye K.A., et al. (2014) Biotechnology. Regulating gene drives. Science 345:626–628.
- Esvelt K.M., et al. Concerning RNA-guided gene drives for the alteration of wild populations. Elife 3:e03401.