Dual-Use Research (Biotechnology and Society 2016)
Watch video (~7 min) Dual Use Research: A Dialogue (NIH Office of Science Policy)
Choose ONE from among these four sets of dual-use case study readings. The first three are from the (Federation of American Scientists) website (Federation of American Scientists).
- Module 2.0 Synthesizing Poliovirus
- Module 4.0 Unexpected Results in Virus Research (Mousepox)
- Module 7.0 Reconstruction of the 1918 Influenza Virus
- Airborne H5N1 flu study
- Polio Czar
- Smallpox Czar
- Flu Czar I (Historical)
- Flu Czar II (Contemporary)
- Read the primary scientific paper describing your assigned study from this list.
- Wimmer E (2006) The test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implications. EMBO Rep 7 Spec No:S3–9. PMID: 16819446
- Moran TM, Isobe H, Fernandez-Sesma A, Schulman JL (1996) Interleukin-4 causes delayed virus clearance in influenza virus-infected mice. J Virol 70:5230–5. PMID: 8764032
- Tumpey TM et al. (2005) Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 310:77–80. PMID: 16210530
- Herfst S et al. (2012) Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336:1534–41. PMID: 22723413
- Research the main human virus relevant for your study: Polio, Smallpox, 1918 Spanish flu, or H5N1 avian flu
- When was the disease prevalent? What danger does it pose in today's world?
- Find a popular science article or news story on the public response to the research that was published at the time when it occurred.