Difference between revisions of "Analog Genetic Circuits (Microbes as Machines)"

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[[File:repressilator_plasmids.png|400px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]]  
 
[[File:repressilator_plasmids.png|400px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]]  
  
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==== [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
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==== [[Media:Spring2015_Analog_Genetic_Circuits_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ====
  
 
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#Gardner2000 pmid=10659857
 
#Gardner2000 pmid=10659857
 
// Describes an artificial "toggle switch" circuit.
 
// Describes an artificial "toggle switch" circuit.
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#Anderson2014 Overview of the Toggle Switch and Repressilator ([https://www.youtube.com/watch?v=0ksvU6Bckbk YouTube])
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#Anderson2014 Explanation of the toggle switch and repressilator by J. Chris Anderson ([https://www.youtube.com/watch?v=0ksvU6Bckbk YouTube])
 
</biblio>
 
</biblio>
  

Latest revision as of 21:35, 16 February 2015

Repressilator [1]. Image from Wikipedia article.

Contents

Download Pre-Discussion Questions (PDF)

Such 'rational network design' may lead both to the engineering of new cellular behaviours and to an improved understanding of naturally occurring networks [2].

Required Reading/Viewing

Error fetching PMID 10659856:
Error fetching PMID 10659857:
  1. Error fetching PMID 10659856: [Elowitz2000]
    Describes the artificial "repressilator" circuit. Also, view the movie of it in action.
  2. Error fetching PMID 10659857: [Gardner2000]
    Describes an artificial "toggle switch" circuit.
  3. Explanation of the toggle switch and repressilator by J. Chris Anderson (YouTube) [Anderson2014]
All Medline abstracts: PubMed | HubMed

Assigned Papers

Error fetching PMID 19478183:
Error fetching PMID 22178928:
  1. Error fetching PMID 19478183: [Friedland2009]
    Bacteria that can count to three.
  2. Error fetching PMID 22178928: [Prindle2012]
    Synchronization and modulation of oscillations across multiple cell populations.
All Medline abstracts: PubMed | HubMed

Additional Resources

  1. Repressilator in TinkerCell (YouTube) [Chandran2011]
    Movie shows how to create and model the repressilator in TinkerCell
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