Difference between revisions of "Analog Genetic Circuits (Microbes as Machines)"

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(Created page with "==== Download Pre-Discussion Questions (PDF) ==== File:Synthia_Genome.png|300px|thumb|right|Construc...")
 
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==== [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
 
==== [[Media:Spring2015_DNA_Assembly_Methods_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
  
[[File:Synthia_Genome.png|300px|thumb|right|Construction of the synthetic genome of ''Mycoplasma laboratorium'' <cite>Gibson2010</cite>.]]  
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[[File:repressilator_plasmids.png|300px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]]  
  
 
<blockquote>
 
<blockquote>
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#Elowitz2000 pmid=10659856
 
#Elowitz2000 pmid=10659856
 
// Describes the artificial "repressilator" circuit.
 
// Describes the artificial "repressilator" circuit.
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#Anderson2014 Toggle Switch and Repressilator ([https://www.youtube.com/watch?v=0ksvU6Bckbk YouTube])
 
</biblio>
 
</biblio>
  
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#Prindle2012 pmid=22178928
 
#Prindle2012 pmid=22178928
 
// Synchronization and modulation of oscillations across multiple cell populations.
 
// Synchronization and modulation of oscillations across multiple cell populations.
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</biblio>
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= Additional Resources =
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<biblio>
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#Chandran2011 Repressilator in TinkerCell([https://www.youtube.com/watch?v=23NTnICU0qw YouTube])
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// Movie shows how to create and model the repressilator in TinkerCell
 
</biblio>
 
</biblio>

Revision as of 05:39, 16 February 2015

Contents

Download Pre-Discussion Questions (PDF)

Repressilator [1]. Image from Wikipedia article.
The only DNA in the cells is the designed synthetic DNA sequence, including “watermark” sequences and other designed gene deletions and polymorphisms, and mutations acquired during the building process [2].

Required Reading/Viewing

Error fetching PMID 10659856:
  1. Error fetching PMID 10659856: [Elowitz2000]
    Describes the artificial "repressilator" circuit.
  2. Toggle Switch and Repressilator (YouTube) [Anderson2014]

Assigned Papers

Error fetching PMID 22178928:
  1. Error fetching PMID 22178928: [Prindle2012]
    Synchronization and modulation of oscillations across multiple cell populations.

Additional Resources

  1. Repressilator in TinkerCell(YouTube) [Chandran2011]
    Movie shows how to create and model the repressilator in TinkerCell