Difference between revisions of "BioBricks and Standardized Genetic Parts (Microbes as Machines)"

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(Required Reading)
(Assigned Papers)
 
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[[File:StandardBioBrickAssembly.png|400px|thumb|right|Standard BioBrick Assembly (image from [http://partsregistry.org/Assembly:Standard_assembly PartsRegistry.org]).]]  
 
[[File:StandardBioBrickAssembly.png|400px|thumb|right|Standard BioBrick Assembly (image from [http://partsregistry.org/Assembly:Standard_assembly PartsRegistry.org]).]]  
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==== [[Media:Spring2015_BioBricks_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
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<blockquote>
 
<blockquote>
<font size="4">[T]he engineering of biology remains complex because we have never made it simple.</font><br> --attributed to Tom Knight <cite>Endy2005</cite>
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<font size="4">[T]he engineering of biology remains complex because we have never made it simple.</font><br>''--attributed to Tom Knight''
 
</blockquote>
 
</blockquote>
  
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<biblio>
 
<biblio>
#BiologicalPartsWikiPage [[CH391L/S14/BiologicalpartsandtheiGEMregistry|Biological Parts and the iGEM Registry]]
 
 
#Knight2003 Knight T ''Idempotent Vector Design for Standard Assembly of Biobricks'' 2005 [http://dspace.mit.edu/handle/1721.1/21168 http://dspace.mit.edu/handle/1721.1/21168]  
 
#Knight2003 Knight T ''Idempotent Vector Design for Standard Assembly of Biobricks'' 2005 [http://dspace.mit.edu/handle/1721.1/21168 http://dspace.mit.edu/handle/1721.1/21168]  
 
// Classic paper first describing BioBricks.
 
// Classic paper first describing BioBricks.
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= Assigned Papers =
 
= Assigned Papers =
 
<biblio>
 
<biblio>
#Canton2008 pmid=18612302
 
// <who is assigned>
 
 
#Anderson2010 pmid=20205762
 
#Anderson2010 pmid=20205762
// <who is assigned>
 
 
#Alnahhas2014 pmid=25525459
 
#Alnahhas2014 pmid=25525459
// <who is assigned>
 
 
</biblio>
 
</biblio>
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= Supplementary Information =
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* [https://www.youtube.com/watch?v=aA5fyWJh5S0 Movie of restriction enzyme EcoR1]
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* [https://www.youtube.com/watch?v=F1mXoy1-Vr0 Presentation describing BioBrick Standard Assembly (J. Christopher Anderson)]

Latest revision as of 03:47, 3 February 2015

Standard BioBrick Assembly (image from PartsRegistry.org).

Contents

Download Pre-Discussion Questions (PDF)

[T]he engineering of biology remains complex because we have never made it simple.
--attributed to Tom Knight

Required Reading

Error fetching PMID 16306983:
Error fetching PMID 24811510:
  1. Knight T Idempotent Vector Design for Standard Assembly of Biobricks 2005 http://dspace.mit.edu/handle/1721.1/21168 [Knight2003]
    Classic paper first describing BioBricks.
  2. Error fetching PMID 16306983: [Endy2005]
    Describes how synthetic biology perspective differs from "mere" recombinant DNA technology and metabolic engineering. Introduces key concepts such as standardization, decoupling, abstraction,
  3. Error fetching PMID 24811510: [Vilanova2014]
    Overview of the iGEM competition.
All Medline abstracts: PubMed | HubMed

Assigned Papers

Error fetching PMID 20205762:
Error fetching PMID 25525459:
  1. Error fetching PMID 20205762: [Anderson2010]
  2. Error fetching PMID 25525459: [Alnahhas2014]
All Medline abstracts: PubMed | HubMed

Supplementary Information