CH391L/S14/Introduction
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Contents |
Introduction to Synthetic Biology
Overview of course structure and topics
CH391L Spring 2014 Course Syllabus
Introduce the Format of course, grading, and policies.
Synthetic biology concept map
ethics [video?], challenges [video?], and future [video?].
Timeline of Synthetic Biology
Year | Event |
---|---|
1970 | Discovery of first site-specific restriction enzyme [1] |
1972 | First publication on recombinant DNA [2] |
1976 | First genome sequenced- Bacteriophage MS2 [3] |
1981 | Introduction of phosphoramidite method of DNA oligonucleotide synthesis. [4] |
1983 | First genetically modified plant is produced [5] |
2000 | The "Repressilator" [6] |
2002 | Creation of the first synthetic virus [7] |
2003 | First use of the term "BioBrick" [8] First chemically synthesized bacteriophage genome assembled [9] |
2004 | First iGEM Jamboree |
2005 | "Adventures in Synthetic Biology" Nature Cover |
2006 | Human Genome Project completed [10] |
2007 | First application of context-free grammars in CAD software for Synthetic Biology (GenoCAD) [11] |
2008 | First synthetic genome assembled [12] |
2010 | Creation of Mycoplasma mycoides JCVI-syn1.0, the first microbe with a self-replicating synthetic genome. [13] |
2012 | Storage of digital information using DNA popularized in the media, Economist (Archives Could Last Thousands of Years when Stored on DNA) |
Wiki editing
Examples from Spring 2013:
Ancestral Sequence Reconstruction
How to edit a wiki: Instructions for Wiki Editing
Ethics and standards
- Do NOT delete other people's work or comments.
- Always preview your changes before saving them.
- DO NOT use copyrighted material unless you have permission.
- ALWAYS CITE material or concepts used from sources;DO NOT PLAGIARIZE