Difference between revisions of "Cloning versus Stem Cell Therapies (Biotechnology and Society 2016)"
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==== Required Reading/Viewing ==== | ==== Required Reading/Viewing ==== | ||
− | * http://content.iospress.com/articles/journal-of-parkinsons-disease/jpd160798 | + | * [https://www.michaeljfox.org/understanding-parkinsons/living-with-pd/topic.php?stem-cells Stem Cells and Parkinson's Disease] at the Michael J. Fox Institute<br>This is a good resource for getting a basic understanding of the cause of Parkinson's disease. Also click around and look at other treatment options under "Understanding Parkinsons". For example, [https://www.michaeljfox.org/understanding-parkinsons/living-with-pd/topic.php?medication-motor-symptoms medications for motor symptoms]. |
− | * https://clinicaltrials.gov/ct2/results?term=stem+cells+AND+parkinson%27s | + | * Barker, R. A., Drouin-Ouellet, J., Parmar, M. (2015) [https://www.ncbi.nlm.nih.gov/pubmed/26240036 Cell-based therapies for Parkinson disease—past insights and future potential.] ''Nat. Rev. Neurol.'' '''11''': 492–503.<br>Comprehensive review of subject. |
+ | * Barker, R. A., Parmar, M., Kirkeby, A., Björklund, A., Thompson, L., Brundin, P. (2016) [http://content.iospress.com/articles/journal-of-parkinsons-disease/jpd160798 Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016?] ''J. Parkinsons. Dis.'' '''6''': 57–63.<br>Up to the minute updates. | ||
+ | * [https://clinicaltrials.gov/ct2/results?term=stem+cells+AND+parkinson%27s List of current clinical trial's for Parkinson's Disease involving stem cells] | ||
== Organ Regeneration Czar == | == Organ Regeneration Czar == |
Revision as of 20:19, 28 October 2016
Download Pre-Discussion Questions (MS Word)
Download Policy Czar Template (MS Word)
Everyone: Dolly the Sheep and Pet Cloning
Required Reading/Viewing
- Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385:810–813.
Paper describing cloning of Dolly the sheep. - Stewart C (1997) Nuclear transplantation. An udder way of making lambs. Nature 385:769, 771.
News and Views article accompanying Dolly article. - Pera M, Trounson A (2013) Cloning debate: Stem-cell researchers must stay engaged. Nature 498:159–161.
Compares the development of ESC, SCNT, and iPSC technologies and mentions some applications. - My Friend Again: Pet Cloning Service
See especially, the "My Dog has died" link.
Additional Resources
- The Dark Side of Pet Cloning Emily Singer MIT Technology Review. January 30, 2009.
Comment about pet cloning services. - This American Life piece on (Second) Chance the cloned Bull
- How Cloning Works
Hwang Woo-suk Czar
Required Reading/Viewing
- Cyranoski D (2014) Cloning comeback. Nature 505:468–471.
Story of the career of Woo Suk Hwang. - Hwang WS et al. (2005) Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 308:1777–1783.
Check out the paper and the follow-up retraction. - Be sure to describe specifically what the scientific misconduct was for the two major studies and what the penalties were.
Parkinson's Czar
Required Reading/Viewing
- Stem Cells and Parkinson's Disease at the Michael J. Fox Institute
This is a good resource for getting a basic understanding of the cause of Parkinson's disease. Also click around and look at other treatment options under "Understanding Parkinsons". For example, medications for motor symptoms. - Barker, R. A., Drouin-Ouellet, J., Parmar, M. (2015) Cell-based therapies for Parkinson disease—past insights and future potential. Nat. Rev. Neurol. 11: 492–503.
Comprehensive review of subject. - Barker, R. A., Parmar, M., Kirkeby, A., Björklund, A., Thompson, L., Brundin, P. (2016) Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016? J. Parkinsons. Dis. 6: 57–63.
Up to the minute updates. - List of current clinical trial's for Parkinson's Disease involving stem cells