Difference between revisions of "Cloning versus Stem Cell Therapies (Biotechnology and Society 2016)"

Latest revision as of 00:31, 30 October 2016

Taxidermied remains of Dolly, the first cloned mammal. (Image source)

Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385:810–813.
Paper describing cloning of Dolly the sheep.
Stewart C (1997) Nuclear transplantation. An udder way of making lambs. Nature 385:769, 771.
News and Views article accompanying Dolly article.
Pera M, Trounson A (2013) Cloning debate: Stem-cell researchers must stay engaged. Nature 498:159–161.
Compares the development of ESC, SCNT, and iPSC technologies and mentions some applications.
My Friend Again: Pet Cloning Service
See especially, the "My Dog has died" link.

Cyranoski D (2014) Cloning comeback. Nature 505:468–471.
Story of the career of Woo Suk Hwang.
Hwang WS et al. (2005) Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 308:1777–1783.
Check out the paper and the follow-up retraction.
Be sure to describe specifically what the scientific misconduct was for the two major studies and what the penalties were.

Stem Cells and Parkinson's Disease at the Michael J. Fox Institute
This is a good resource for getting a basic understanding of the cause of Parkinson's disease. Also click around and look at other treatment options under "Understanding Parkinsons". For example, medications for motor symptoms.
Barker, R. A., Drouin-Ouellet, J., Parmar, M. (2015) Cell-based therapies for Parkinson disease—past insights and future potential. Nat. Rev. Neurol. 11: 492–503.
Comprehensive review of subject.
Barker, R. A., Parmar, M., Kirkeby, A., Björklund, A., Thompson, L., Brundin, P. (2016) Are Stem Cell-Based Therapies for Parkinson’s Disease Ready for the Clinic in 2016? J. Parkinsons. Dis. 6: 57–63.
Up to the minute updates.
List of current clinical trial's for Parkinson's Disease involving stem cells

Focus on treatment of myocardial infarction and related heart disease.

Eight tiny organs grown by scientists Euro Stem Cell.
Why might you want to grow a tiny organ?

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 [[File:Dolly.jpg|380px|thumb|right|Taxidermied remains of Dolly, the first cloned mammal. ([http://www.flickr.com/photos/aur2899/5757941599/ Image source])]]
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