Difference between revisions of "Digital Genetic Circuits (Microbes as Machines)"

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// Describes using recombinases to implement digital logic in bacteria.
 
// Describes using recombinases to implement digital logic in bacteria.
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// Accompanying perspective article.
 
// Accompanying perspective article.
 
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// Scalable system for recording "cellular memories" in a genome.
 
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Revision as of 20:01, 22 February 2015

Example of a logic gate from [1].

Contents

Download Pre-Discussion Questions (PDF)

These gates are perhaps the farthest away from any natural counterpart and are thus likely to occupy synthetic and systems biologists in the years to come.[2].

Required Reading/Viewing

Error fetching PMID 23539178:
Error fetching PMID 23641100:
  1. Error fetching PMID 23539178: [Bonnet2013]
    Describes using recombinases to implement digital logic in bacteria.
  2. Error fetching PMID 23641100: [Benenson2013]
    Accompanying perspective article.
All Medline abstracts: PubMed | HubMed

Assigned Papers

Error fetching PMID 25395541:
  1. Error fetching PMID 25395541: [Farzadfard2015]
    Scalable system for recording "cellular memories" in a genome.

Additional Resources

  1. Transcriptors & Boolean Integrase Logic (BIL) gates, explained (YouTube) [Endy2013]
    Movie describing the results of the Bonnet2013 paper