Difference between revisions of "Do-It-Yourself (DIY) Biology versus Bioterrorism (Biotechnology and Society 2016)"
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(→4. Anthrax Case Czar) |
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− | == | + | [[File:BioluminescentNicotiana.png|500px|thumb|right|Bioluminescent ''Nicotiana tabacum'' (tobacco). From Krichevsky et al. 2010.]] |
+ | == Required Reading/Viewing == | ||
+ | ==== [[Media:DIY_Biology_Versus_Bioterrorism_Pre-Discussion_Questions_2016F.pdf| Download Pre-Discussion Questions (PDF)]] ==== | ||
− | + | #Jorgensen [http://www.ted.com/talks/ellen_jorgensen_biohacking_you_can_do_it_too.html Ellen Jorgensen TED Talk] "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace. | |
− | # | + | # Jefferson C, Lentzos F, Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. ''Front. Public Health.'' '''2''':115. [http://www.ncbi.nlm.nih.gov/pubmed/25191649 PMID: 25191649 ] |
− | // General review of history of biowarfare and bioterrorism. | + | |
− | + | == Czar Assignments == | |
− | + | ==== [[Media:Policy_Czar_Template.docx | Download Policy Czar Template (MS Word)]] ==== | |
− | + | ||
+ | === 1. DIY/Biohacking Czar === | ||
+ | * What types of projects do most citizen scientists pursue at BioMaker spaces? What types of training and equipment are available? | ||
+ | * Prominent BioMaker spaces: [http://genspace.org/ GenSpace (NYC)] | [http://biocurious.org/ BioCurious (Bay Area)] | ||
+ | * Kelty CM. (2010) Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today. ''J. Sci. Comm.'' '''9''':1-8. [http://jcom.sissa.it/archive/09/01/Jcom0901(2010)C01/Jcom0901(2010)C03 Available online here.] Contains several examples of citizen scientist projects. | ||
+ | * Search for new citizen scientist or DIY biology projects on sites like: [https://experiment.com/ Experiment.com] and [https://www.indiegogo.com/ Indigogo.com]. Here are some to get you started: [https://www.kickstarter.com/projects/339005690/bento-lab-a-dna-laboratory-for-everybody Bento lab] and [https://www.indiegogo.com/projects/diy-crispr-kits-learn-modern-science-by-doing#/ DIY CRISPR] | ||
+ | * What is the relationship between some example projects and potential bioterrorism/biosecurity threats? | ||
+ | |||
+ | === 2. Glowing Plant Czar === | ||
+ | * What is this project? What is the product and how will it be created? | ||
+ | * The project has been ongoing for several years now. What progress has been made? What hurdles remain to fully achieving the original goals? | ||
+ | * Describe how this project was ahead of current government regulations and Kickstarter's terms of service when it first started. How have both reacted to this project? | ||
+ | * [http://www.kickstarter.com/projects/antonyevans/glowing-plants-natural-lighting-with-no-electricit Glowing Plants: Natural Lighting with no Electricity (Kickstarter)] | ||
+ | * [http://www.glowingplant.com Glowing Plant website]. | ||
+ | * [http://tmblr.co/ZgwW5urtZ_x_ Blog post about regulations covering Glowing Plants.] | ||
+ | * Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminescent plants. ''PLoS One'' '''5''':e15461. [http://www.ncbi.nlm.nih.gov/pubmed/21103397 PMID: 21103397] Scientific paper covering how bioluminescent ''Nicotiana'' was created. (Similar to methods used by the "Glowing Plants" project.) | ||
+ | * [http://splasho.com/blog/2013/04/27/crowd-funding-avatar Post on "Crowd Funding Avatar" (Splasho)] // Detailed blog post putting the Kickstarter project's science and role in DIY biology in context. | ||
+ | |||
+ | === 3. Bioterrorism Czar === | ||
+ | |||
+ | * What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks). | ||
+ | * What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk? | ||
+ | * What types of responses is the U.S. prepared for if a bioterrorism incident occurs? | ||
+ | * Riedel S (2004) Biological warfare and bioterrorism: a historical review. ''Proc. Baylor Univ. Med. Cent.'' '''17''':400–406. [http://www.ncbi.nlm.nih.gov/pubmed/16200127 PMID: 16200127] // General review of history of biowarfare and bioterrorism. | ||
+ | * TDSHS [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // In-depth history and timelines that are useful for thinking about historical examples to highlight. | ||
+ | |||
+ | === 4. Anthrax Case Czar === | ||
+ | * Describe the history of Anthrax as a bioterrorism agent. | ||
+ | * Give a timeline of the Anthrax case and put it in historical context. | ||
+ | * What is the evidence that Bruce Ivins was the source of the Anthrax letters? | ||
+ | * [https://vault.fbi.gov/Amerithrax American Anthrax Investigation Documents (FBI)] // Report on the anthrax case where letters containing spores were sent to government officials after 9/11/2001. | ||
+ | * [http://www.nytimes.com/topic/subject/anthrax Related articles at NYT] These include more recent examples of incorrect Anthrax shipments. They include a [http://www.nytimes.com/slideshow/2009/01/03/world/20090104-anthrax_index.html?rref=collection%2Ftimestopic%2FAnthrax&action=click&contentCollection=timestopics®ion=stream&module=stream_unit&version=latest&contentPlacement=42&pgtype=collection&_r=0 Slide Show related to the Anthrax case timeline] |
Latest revision as of 14:39, 11 September 2016
Contents |
Required Reading/Viewing
Download Pre-Discussion Questions (PDF)
- Jorgensen Ellen Jorgensen TED Talk "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
- Jefferson C, Lentzos F, Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. Front. Public Health. 2:115. PMID: 25191649
Czar Assignments
Download Policy Czar Template (MS Word)
1. DIY/Biohacking Czar
- What types of projects do most citizen scientists pursue at BioMaker spaces? What types of training and equipment are available?
- Prominent BioMaker spaces: GenSpace (NYC) | BioCurious (Bay Area)
- Kelty CM. (2010) Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today. J. Sci. Comm. 9:1-8. Available online here. Contains several examples of citizen scientist projects.
- Search for new citizen scientist or DIY biology projects on sites like: Experiment.com and Indigogo.com. Here are some to get you started: Bento lab and DIY CRISPR
- What is the relationship between some example projects and potential bioterrorism/biosecurity threats?
2. Glowing Plant Czar
- What is this project? What is the product and how will it be created?
- The project has been ongoing for several years now. What progress has been made? What hurdles remain to fully achieving the original goals?
- Describe how this project was ahead of current government regulations and Kickstarter's terms of service when it first started. How have both reacted to this project?
- Glowing Plants: Natural Lighting with no Electricity (Kickstarter)
- Glowing Plant website.
- Blog post about regulations covering Glowing Plants.
- Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminescent plants. PLoS One 5:e15461. PMID: 21103397 Scientific paper covering how bioluminescent Nicotiana was created. (Similar to methods used by the "Glowing Plants" project.)
- Post on "Crowd Funding Avatar" (Splasho) // Detailed blog post putting the Kickstarter project's science and role in DIY biology in context.
3. Bioterrorism Czar
- What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks).
- What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
- What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
- Riedel S (2004) Biological warfare and bioterrorism: a historical review. Proc. Baylor Univ. Med. Cent. 17:400–406. PMID: 16200127 // General review of history of biowarfare and bioterrorism.
- TDSHS History of Bioterrorism (Texas Department of State Health Services) // In-depth history and timelines that are useful for thinking about historical examples to highlight.
4. Anthrax Case Czar
- Describe the history of Anthrax as a bioterrorism agent.
- Give a timeline of the Anthrax case and put it in historical context.
- What is the evidence that Bruce Ivins was the source of the Anthrax letters?
- American Anthrax Investigation Documents (FBI) // Report on the anthrax case where letters containing spores were sent to government officials after 9/11/2001.
- Related articles at NYT These include more recent examples of incorrect Anthrax shipments. They include a Slide Show related to the Anthrax case timeline