Difference between revisions of "Do-It-Yourself (DIY) Biology versus Bioterrorism (Biotechnology and Society 2016)"

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(4. Anthrax Czar)
(4. Anthrax Case Czar)
 
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==== [[Media:DIY_Biology_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
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[[File:BioluminescentNicotiana.png|500px|thumb|right|Bioluminescent ''Nicotiana tabacum'' (tobacco). From Krichevsky et al. 2010.]]  
 
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== Required Reading/Viewing ==
 
== Required Reading/Viewing ==
[[File:BioluminescentNicotiana.png|500px|thumb|right|Bioluminescent ''Nicotiana tabacum'' (tobacco). From Krichevsky et al. 2010 ]]  
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==== [[Media:DIY_Biology_Versus_Bioterrorism_Pre-Discussion_Questions_2016F.pdf| Download Pre-Discussion Questions (PDF)]] ====
  
 
#Jorgensen [http://www.ted.com/talks/ellen_jorgensen_biohacking_you_can_do_it_too.html Ellen Jorgensen TED Talk] "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
 
#Jorgensen [http://www.ted.com/talks/ellen_jorgensen_biohacking_you_can_do_it_too.html Ellen Jorgensen TED Talk] "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
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* Describe how this project was ahead of current government regulations and Kickstarter's terms of service when it first started. How have both reacted to this project?
 
* Describe how this project was ahead of current government regulations and Kickstarter's terms of service when it first started. How have both reacted to this project?
 
* [http://www.kickstarter.com/projects/antonyevans/glowing-plants-natural-lighting-with-no-electricit Glowing Plants: Natural Lighting with no Electricity (Kickstarter)]  
 
* [http://www.kickstarter.com/projects/antonyevans/glowing-plants-natural-lighting-with-no-electricit Glowing Plants: Natural Lighting with no Electricity (Kickstarter)]  
* [http://glowingplant.com‎ Glowing Plant website].  
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* [http://www.glowingplant.com Glowing Plant website].  
* [http://tmblr.co/ZgwW5urtZ_x_ Blog post about regulations covering Glowing Plants.] Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminescent plants. ''PLoS One'' '''5''':e15461. [http://www.ncbi.nlm.nih.gov/pubmed/21103397 PMID: 21103397] Scientific paper covering how bioluminescent ''Nicotiana'' was created. (Similar to methods used by the "Glowing Plants" project.)  
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* [http://tmblr.co/ZgwW5urtZ_x_ Blog post about regulations covering Glowing Plants.]  
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* Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminescent plants. ''PLoS One'' '''5''':e15461. [http://www.ncbi.nlm.nih.gov/pubmed/21103397 PMID: 21103397] Scientific paper covering how bioluminescent ''Nicotiana'' was created. (Similar to methods used by the "Glowing Plants" project.)  
 
* [http://splasho.com/blog/2013/04/27/crowd-funding-avatar Post on "Crowd Funding Avatar" (Splasho)] // Detailed blog post putting the Kickstarter project's science and role in DIY biology in context.
 
* [http://splasho.com/blog/2013/04/27/crowd-funding-avatar Post on "Crowd Funding Avatar" (Splasho)] // Detailed blog post putting the Kickstarter project's science and role in DIY biology in context.
  
 
=== 3. Bioterrorism Czar ===
 
=== 3. Bioterrorism Czar ===
  
* What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks). Examples could be: ricin,
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* What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks).
 
* What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
 
* What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
 
* What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
 
* What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
* Riedel S (2004) Biological warfare and bioterrorism: a historical review. ''Proc. Baylor Univ. Med. Cent. '''17''':400–406. [http://www.ncbi.nlm.nih.gov/pubmed/16200127 PMID: 16200127] // General review of history of biowarfare and bioterrorism.
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* Riedel S (2004) Biological warfare and bioterrorism: a historical review. ''Proc. Baylor Univ. Med. Cent.'' '''17''':400–406. [http://www.ncbi.nlm.nih.gov/pubmed/16200127 PMID: 16200127] // General review of history of biowarfare and bioterrorism.
 
* TDSHS  [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // In-depth history and timelines that are useful for thinking about historical examples to highlight.
 
* TDSHS  [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // In-depth history and timelines that are useful for thinking about historical examples to highlight.
  
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* Give a timeline of the Anthrax case and put it in historical context.
 
* Give a timeline of the Anthrax case and put it in historical context.
 
* What is the evidence that Bruce Ivins was the source of the Anthrax letters?
 
* What is the evidence that Bruce Ivins was the source of the Anthrax letters?
* [http://www.justice.gov/amerithrax/ American Anthrax Investigation Documents (FBI)]  // Report on the  anthrax case where letters containing spores were sent to government officials after 9/11/2001.
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* [https://vault.fbi.gov/Amerithrax American Anthrax Investigation Documents (FBI)]  // Report on the  anthrax case where letters containing spores were sent to government officials after 9/11/2001.
* [http://www.nytimes.com/topic/subject/anthrax Related articles at NYT] These include more recent examples of incorrect Anthrax shipments.[http://www.nytimes.com/slideshow/2009/01/03/world/20090104-anthrax_index.html?rref=collection%2Ftimestopic%2FAnthrax&action=click&contentCollection=timestopics&region=stream&module=stream_unit&version=latest&contentPlacement=42&pgtype=collection&_r=0 Slide Show related to the Anthrax case timeline]
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* [http://www.nytimes.com/topic/subject/anthrax Related articles at NYT] These include more recent examples of incorrect Anthrax shipments. They include a [http://www.nytimes.com/slideshow/2009/01/03/world/20090104-anthrax_index.html?rref=collection%2Ftimestopic%2FAnthrax&action=click&contentCollection=timestopics&region=stream&module=stream_unit&version=latest&contentPlacement=42&pgtype=collection&_r=0 Slide Show related to the Anthrax case timeline]

Latest revision as of 14:39, 11 September 2016

Bioluminescent Nicotiana tabacum (tobacco). From Krichevsky et al. 2010.

Contents

Required Reading/Viewing

Download Pre-Discussion Questions (PDF)

  1. Jorgensen Ellen Jorgensen TED Talk "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
  2. Jefferson C, Lentzos F, Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. Front. Public Health. 2:115. PMID: 25191649

Czar Assignments

Download Policy Czar Template (MS Word)

1. DIY/Biohacking Czar

  • What types of projects do most citizen scientists pursue at BioMaker spaces? What types of training and equipment are available?
  • Prominent BioMaker spaces: GenSpace (NYC) | BioCurious (Bay Area)
  • Kelty CM. (2010) Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today. J. Sci. Comm. 9:1-8. Available online here. Contains several examples of citizen scientist projects.
  • Search for new citizen scientist or DIY biology projects on sites like: Experiment.com and Indigogo.com. Here are some to get you started: Bento lab and DIY CRISPR
  • What is the relationship between some example projects and potential bioterrorism/biosecurity threats?

2. Glowing Plant Czar

3. Bioterrorism Czar

  • What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks).
  • What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
  • What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
  • Riedel S (2004) Biological warfare and bioterrorism: a historical review. Proc. Baylor Univ. Med. Cent. 17:400–406. PMID: 16200127 // General review of history of biowarfare and bioterrorism.
  • TDSHS History of Bioterrorism (Texas Department of State Health Services) // In-depth history and timelines that are useful for thinking about historical examples to highlight.

4. Anthrax Case Czar