Difference between revisions of "Do-It-Yourself (DIY) Biology versus Bioterrorism (Biotechnology and Society 2016)"

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= Construction in progress =
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==== [[Media:DIY_Biology_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ====
  
== Additional Background ==
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== Required Reading/Viewing ==
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[[File:BioluminescentNicotiana.png|500px|thumb|right|Bioluminescent ''Nicotiana tabacum'' (tobacco). From Krichevsky et al. 2010 ]]
  
<biblio>
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#Jorgensen [http://www.ted.com/talks/ellen_jorgensen_biohacking_you_can_do_it_too.html Ellen Jorgensen TED Talk] "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
#Riedel2004 pmid=16200127
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# Jefferson C, Lentzos F, Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. ''Front. Public Health.'' '''2''':115. [http://www.ncbi.nlm.nih.gov/pubmed/25191649  PMID:  25191649 ]
// General review of history of biowarfare and bioterrorism.
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#TDSHS  [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // More in-depth history and timelines than the assigned review.
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== Czar Assignments ==
#FBI  [http://www.justice.gov/amerithrax/ American Anthrax Investigation Documents (FBI)]  // Report on the  anthrax case where letters containing spores were sent to government officials after 9/11/2001.
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==== [[Media:Policy_Czar_Template.docx | Download Policy Czar Template (MS Word)]] ====
</biblio>
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=== 1. DIY/Biohacking Czar ===
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* What types of projects do most citizen scientists pursue at BioMaker spaces? What types of training and equipment are available?
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* Prominent BioMaker spaces: [http://genspace.org/ GenSpace (NYC)] | [http://biocurious.org/ BioCurious (Bay Area)]
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* Kelty CM. (2010) Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today. ''J. Sci. Comm.'' '''9''':1-8. [http://jcom.sissa.it/archive/09/01/Jcom0901(2010)C01/Jcom0901(2010)C03 Available online here.] Contains several examples of citizen scientist projects.
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* Search for new citizen scientist or DIY biology projects on sites like: [https://experiment.com/ Experiment.com] and [https://www.indiegogo.com/ Indigogo.com]. Here are some to get you started: [https://www.kickstarter.com/projects/339005690/bento-lab-a-dna-laboratory-for-everybody Bento lab] and [https://www.indiegogo.com/projects/diy-crispr-kits-learn-modern-science-by-doing#/ DIY CRISPR]
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* What is the relationship between some example projects and potential bioterrorism/biosecurity threats?
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=== 2. Glowing Plant Czar ===
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* What is this project? What is the product and how will it be created?
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* The project has been ongoing for several years now. What progress has been made? What hurdles remain to fully achieving the original goals?
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* Describe how this project was ahead of current government regulations and Kickstarter's terms of service when it first started. How have both reacted to this project?
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* [http://www.kickstarter.com/projects/antonyevans/glowing-plants-natural-lighting-with-no-electricit Glowing Plants: Natural Lighting with no Electricity (Kickstarter)]
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* [http://glowingplant.com‎ Glowing Plant website].
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* [http://tmblr.co/ZgwW5urtZ_x_ Blog post about regulations covering Glowing Plants.] Krichevsky A, Meyers B, Vainstein A, Maliga P, Citovsky V (2010) Autoluminescent plants. ''PLoS One'' '''5''':e15461. [http://www.ncbi.nlm.nih.gov/pubmed/21103397 PMID: 21103397] Scientific paper covering how bioluminescent ''Nicotiana'' was created. (Similar to methods used by the "Glowing Plants" project.)
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* [http://splasho.com/blog/2013/04/27/crowd-funding-avatar Post on "Crowd Funding Avatar" (Splasho)] // Detailed blog post putting the Kickstarter project's science and role in DIY biology in context.
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=== 3. Bioterrorism Czar ===
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* What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks). Examples could be: ricin,
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* What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
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* What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
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* Riedel S (2004) Biological warfare and bioterrorism: a historical review. ''Proc. Baylor Univ. Med. Cent. '''17''':400–406. [http://www.ncbi.nlm.nih.gov/pubmed/16200127 PMID: 16200127] // General review of history of biowarfare and bioterrorism.
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* TDSHS  [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // In-depth history and timelines that are useful for thinking about historical examples to highlight.
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=== 4. Anthrax Czar ===
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##FBI  [http://www.justice.gov/amerithrax/ American Anthrax Investigation Documents (FBI)]  // Report on the  anthrax case where letters containing spores were sent to government officials after 9/11/2001.

Revision as of 13:45, 11 September 2016

Contents

Download Pre-Discussion Questions (PDF)

Required Reading/Viewing

Bioluminescent Nicotiana tabacum (tobacco). From Krichevsky et al. 2010
  1. Jorgensen Ellen Jorgensen TED Talk "Biohacking -- you can do it, too." 10 min. Intro to DIY biology by co-founder of GenSpace.
  2. Jefferson C, Lentzos F, Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. Front. Public Health. 2:115. PMID: 25191649

Czar Assignments

Download Policy Czar Template (MS Word)

1. DIY/Biohacking Czar

  • What types of projects do most citizen scientists pursue at BioMaker spaces? What types of training and equipment are available?
  • Prominent BioMaker spaces: GenSpace (NYC) | BioCurious (Bay Area)
  • Kelty CM. (2010) Outlaw, hackers, victorian amateurs: diagnosing public participation in the life sciences today. J. Sci. Comm. 9:1-8. Available online here. Contains several examples of citizen scientist projects.
  • Search for new citizen scientist or DIY biology projects on sites like: Experiment.com and Indigogo.com. Here are some to get you started: Bento lab and DIY CRISPR
  • What is the relationship between some example projects and potential bioterrorism/biosecurity threats?

2. Glowing Plant Czar

3. Bioterrorism Czar

  • What are the biggest historical examples of bioterrorism . Choose 2-3 to research in more detail (excluding the Anthrax attacks). Examples could be: ricin,
  • What are the biggest current concerns of the biosecurity community? Who are the most likely and least likely perpetrators? What is the risk?
  • What types of responses is the U.S. prepared for if a bioterrorism incident occurs?
  • Riedel S (2004) Biological warfare and bioterrorism: a historical review. Proc. Baylor Univ. Med. Cent. 17:400–406. PMID: 16200127 // General review of history of biowarfare and bioterrorism.
  • TDSHS History of Bioterrorism (Texas Department of State Health Services) // In-depth history and timelines that are useful for thinking about historical examples to highlight.

4. Anthrax Czar

    1. FBI American Anthrax Investigation Documents (FBI) // Report on the anthrax case where letters containing spores were sent to government officials after 9/11/2001.