Difference between revisions of "Dual-Use Research (Biotechnology and Society 2016)"

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# [https://fas.org/biosecurity/education/dualuse/FAS_Wimmer/ Module 2.0 Synthesizing Poliovirus]
 
# [https://fas.org/biosecurity/education/dualuse/FAS_Wimmer/ Module 2.0 Synthesizing Poliovirus]
# [https://fas.org/biosecurity/education/dualuse/FAS_Jackson/ Module 4.0 Unexpected Results in Virus Research]
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# [https://fas.org/biosecurity/education/dualuse/FAS_Jackson/ Module 4.0 Unexpected Results in Virus Research (Mousepox)]
 
# [https://fas.org/biosecurity/education/dualuse/FAS_Basler/ Module 7.0 Reconstruction of the 1918 Influenza Virus]
 
# [https://fas.org/biosecurity/education/dualuse/FAS_Basler/ Module 7.0 Reconstruction of the 1918 Influenza Virus]
 
# Airborne H5N1 flu study
 
# Airborne H5N1 flu study
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== Czars ==
 
== Czars ==
  
* Find the primary literature describing the . If there are multiple papers, you may choose one.
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Read the primary scientific paper describing your study from this list.
 
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# Wimmer E (2006) The test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implications. EMBO Rep 7 Spec No:S3–9.
== Required Reading ==
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#
<biblio>
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#
#Wimmer2006 pmid=16819446
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# Herfst S et al. (2012) Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336:1534–41.
//Describes the chemical synthesis of polio virus and the implications for bioterrorism.
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#Herfst2012 pmid=22723413
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// Main scientific paper demonstrating how specific mutations lead H5N1 to become airborne transmissible in ferrets.
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</biblio>
 
</biblio>
  
== Additional Background ==
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Find an article on the public response to the research that was published at the time when it occurred.
 
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<biblio>
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#TDSHS  [http://www.dshs.state.tx.us/preparedness/bt_public_history.shtm History of Bioterrorism (Texas Department of State Health Services)] // More in-depth history and timelines than the assigned review.
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#Maher2012 pmid=22622550 [http://www.nature.com/news/bird-flu-research-the-biosecurity-oversight-1.10695 Available Online] // More discussion of the context of the publication of the airborne H5N1 research.
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#FBI  [http://www.justice.gov/amerithrax/ American Anthrax Investigation Documents (FBI)]  // Report on the anthrax case where letters containing spores were sent to government officials after 9/11/2001.
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</biblio>
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Revision as of 14:19, 29 August 2016

Download Pre-Discussion Questions (PDF)

Required Reading/Viewing

Watch video (~7 min) Dual Use Research: A Dialogue (NIH Office of Science Policy)

Choose ONE among these four dual-use case study readings. The first three are from the (Federation of American Scientists) website (Federation of American Scientists).

  1. Module 2.0 Synthesizing Poliovirus
  2. Module 4.0 Unexpected Results in Virus Research (Mousepox)
  3. Module 7.0 Reconstruction of the 1918 Influenza Virus
  4. Airborne H5N1 flu study
    • Enserink M (2012) Avian influenza. Public at last, H5N1 study offers insight into virus’s possible path to pandemic. Science 336:1494–1497. PMID: 22723387 Read at Science
    • Maher B (2012) Bird-flu research: The biosecurity oversight. Nature 485:431-434. PMID: 22622550 Read at Nature

Czars

Read the primary scientific paper describing your study from this list.

  1. Wimmer E (2006) The test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implications. EMBO Rep 7 Spec No:S3–9.
  2. Herfst S et al. (2012) Airborne transmission of influenza A/H5N1 virus between ferrets. Science 336:1534–41.

</biblio>

Find an article on the public response to the research that was published at the time when it occurred.