Difference between revisions of "Gene Therapy (Biotechnology and Society)"
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==== [[Media:Gene_Therapy_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ==== | ==== [[Media:Gene_Therapy_Pre-Discussion_Questions.pdf| Download Pre-Discussion Questions (PDF)]] ==== | ||
− | [[File: | + | [[File:AAV_Gene_Therapy.jpg|400px|thumb|right|Glybera ([http://en.wikipedia.org/wiki/Alipogene_tiparvovec Alipogene tiparvovec]) gene therapy]] |
== Required Reading/Viewing == | == Required Reading/Viewing == | ||
+ | |||
+ | We will discuss gene therapy for two diseases: SCID (Severe Combined Immunodeficiency Disease) and Familial Lipoprotein Lipase Deficiency (LPLD). | ||
<biblio> | <biblio> | ||
+ | # Carl Zimmer. Gene Therapy emerges from disgrace to be the next big thing, again. Wired Science Blogs. August 13, 2013. | ||
+ | // Read article at [http://www.wired.com/wiredscience/geneticfuture/ wired.com]. | ||
#Bandage2013 [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah. | #Bandage2013 [http://learn.genetics.utah.edu/content/tech/genetherapy/ Gene Therapy: Molecular Bandage?] Educational website at the University of Utah. | ||
// Especially, check out the "Tools of the Trade" and "Space Doctor" links. | // Especially, check out the "Tools of the Trade" and "Space Doctor" links. | ||
#Hacein2008 pmid=18688285 | #Hacein2008 pmid=18688285 | ||
− | // Study characterizing genomes SCID patients who developed Leukemia after successful gene therapy. | + | // Study characterizing the genomes of SCID patients who developed Leukemia after successful gene therapy. Feel free to skim for key details. |
− | # | + | #Bryant2013 pmid=23808604 |
− | // | + | // Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014). |
+ | #Giacca2010 isbn=8847016428 | ||
+ | // [http://link.springer.com/chapter/10.1007/978-88-470-1643-9_5 Read Chapter 5: Ethical and Social Problems of Gene Therapy] | ||
</biblio> | </biblio> | ||
== Additional Resources == | == Additional Resources == | ||
+ | |||
+ | <biblio> | ||
+ | #Griesenbach2011 pmid=21443272 | ||
+ | // Review of developments in gene therapy for cystic fibrosis over the last ~20 years. | ||
+ | #Glybera [http://www.uniqure.com/products/glybera/ Glybera] - commercial gene therapy product available in Europe. | ||
+ | </biblio> |
Latest revision as of 19:29, 28 October 2013
Download Pre-Discussion Questions (PDF)
Required Reading/Viewing
We will discuss gene therapy for two diseases: SCID (Severe Combined Immunodeficiency Disease) and Familial Lipoprotein Lipase Deficiency (LPLD).
Error fetching PMID 18688285:
Error fetching PMID 23808604:
Error fetching PMID 23808604:
- Zimmer. Gene Therapy emerges from disgrace to be the next big thing, again. Wired Science Blogs. August 13, 2013.
Read article at wired.com. - Gene Therapy: Molecular Bandage? Educational website at the University of Utah.
Especially, check out the "Tools of the Trade" and "Space Doctor" links. - Error fetching PMID 18688285:
Study characterizing the genomes of SCID patients who developed Leukemia after successful gene therapy. Feel free to skim for key details. - Error fetching PMID 23808604:
Chronicles the development of the first commercially available gene therapy treatment (available in the U.S. in fall 2014). - ISBN:8847016428
Additional Resources
Error fetching PMID 21443272:
- Error fetching PMID 21443272:
Review of developments in gene therapy for cystic fibrosis over the last ~20 years. - Glybera - commercial gene therapy product available in Europe.