Difference between revisions of "Metabolic Engineering (Microbes as Machines)"

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Revision as of 19:24, 8 March 2015

Using synthetic biology to produce artemisinin [1].

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However, it is not possible to chemically synthesize all natural products in an economical manner, despite advances in synthetic organic chemistry during the past century; for example, the potent antimalarial drug precursor artemisinin cannot be economically produced by chemical synthesis alone [2].

Required Reading/Viewing

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  1. Error fetching PMID 24686413: [Paddon2014]
    Summary of how economical semi-synthetic production of artemisinin was achieved in engineered yeast

Assigned Papers

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Error fetching PMID 24038353:
Error fetching PMID 22509035:
  1. Error fetching PMID 25247316: [Quandti2014]
    Addicting E. coli to caffeine by metabolic engineering
  2. Error fetching PMID 24038353: [Lee2013]
    Optimizing the production of different chromophores by altering the violacein pathway
  3. Error fetching PMID 22509035: [Temme2012]
    Refactoring a nitrogen fixation gene cluster
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