Difference between revisions of "Metabolic Engineering (Microbes as Machines)"
From SynBioCyc
(Created page with "Using synthetic biology to produce artemisinin <cite>Basu2005</cite>. ==== Media:Spring2015_Metabolic_Engineering_Pre-Dis...") |
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| − | [[File:Paddon_artemisinin_flask.png|thumb|right|Using synthetic biology to produce artemisinin <cite> | + | [[File:Paddon_artemisinin_flask.png|thumb|right|Using synthetic biology to produce artemisinin <cite> Paddon2014 </cite>.]] |
==== [[Media:Spring2015_Metabolic_Engineering_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ==== | ==== [[Media:Spring2015_Metabolic_Engineering_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ==== | ||
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#Paddon2014 pmid=24686413 | #Paddon2014 pmid=24686413 | ||
// Summary of how economical semi-synthetic production of artemisinin was achieved in engineered yeast | // Summary of how economical semi-synthetic production of artemisinin was achieved in engineered yeast | ||
| + | #JBEI2013 Turning Sugar into High Performance Fuel: CNN's The Next List Profiles Jay Keasling ([https://www.youtube.com/watch?v=e7kC0knLaW8 Watch on YouTube]) | ||
| + | // CNN Interview with Jay Keasling that mentions artemisinin and also focuses on biofuels. | ||
</biblio> | </biblio> | ||
Revision as of 19:53, 8 March 2015
Download Pre-Discussion Questions (PDF)
However, it is not possible to chemically synthesize all natural products in an economical manner, despite advances in synthetic organic chemistry during the past century; for example, the potent antimalarial drug precursor artemisinin cannot be economically produced by chemical synthesis alone [1].
Required Reading/Viewing
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Summary of how economical semi-synthetic production of artemisinin was achieved in engineered yeast - Turning Sugar into High Performance Fuel: CNN's The Next List Profiles Jay Keasling (Watch on YouTube)
CNN Interview with Jay Keasling that mentions artemisinin and also focuses on biofuels.
Assigned Papers
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Addicting E. coli to caffeine by metabolic engineering - Error fetching PMID 24038353:
Optimizing the production of different chromophores by altering the violacein pathway - Error fetching PMID 22509035:
Refactoring a nitrogen fixation gene cluster
