Probiotics and the Human Microbiome (Biotechnology and Society)

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We will concentrate on discussing two examples where probiotic microbes could be used to modify the normal human microbiome, to "cure" cavities and obesity.

Required Reading

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  1. Jonathan Eisen TED Talk. "Meet your mIcrobes." April 2012 (15 min). [Eisen2012]
    Introduction to the human microbiome and probiotics.
    View on ted.com
  2. Zimmer, C. Tending the Body’s Microbial Garden. New York Times June 18, 2012. [Zimmer2012]
    Overview of recent microbiome studies.
    Article at NYT Human Microbiome Infographic
  3. Error fetching PMID 12369203: [Hillman2002]
    Review paper describing the initial development of a probiotic bacterial strain to prevent cavities.
  4. Greenwood, V. "You Are Your Bacteria: How the Gut Microbiome Influences Health." TIME.com Aug. 29, 2013 [Greenwood2013]
    Article on TIME.com
  5. Error fetching PMID 23985869: [Fang2013]
    News and Views describing two studies of the relationship between obesity and the gut microbiota.
  6. Error fetching PMID 23985870: [LeChatelier2013]
    One of the two studies linking the level of microbial diversity in the gut to obesity associated diseases.
All Medline abstracts: PubMed | HubMed

Additional Resources