Difference between revisions of "Producing Biomaterials (Microbes as Machines)"

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(Created page with "Using synthetic biology to produce artemisinin <cite> Paddon2014 </cite>. ==== Media:Spring2015_Biomaterials_Pre-Discussi...")
 
(→‎Assigned Papers)
 
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[[File:Paddon_artemisinin_flask.png|thumb|right|Using synthetic biology to produce artemisinin <cite> Paddon2014 </cite>.]]  
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[[File:Xia_spider_silk_filaments.png|thumb|300px|right|Silk fibers spun from recombinant protein expressed in 'E. coli' <cite> Xia2010 </cite>.]]  
  
 
==== [[Media:Spring2015_Biomaterials_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ====
 
==== [[Media:Spring2015_Biomaterials_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ====
  
 
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<font size="4">However, it is not possible to chemically synthesize all natural products in an economical manner, despite advances in synthetic organic chemistry during the past century; for example, the potent antimalarial drug precursor artemisinin cannot be economically produced by chemical synthesis alone <cite> Paddon2014 </cite>.</font>
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<font size="4">The fibre spun with the native-sized recombinant spider silk protein showed similar mechanical properties to native spider silk, thus opening the possibility of its wide range of industrial and biomedical applications. <cite> Xia2010 </cite>.</font>
 
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<biblio>
 
<biblio>
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#Paddon2014 pmid=24686413
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#Xia2010 pmid=20660779
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// Summary of how economical semi-synthetic production of artemisinin was achieved in engineered yeast
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// Production of spider silk in ''E. coli''.
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#JBEI2013 Turning Sugar into High Performance Fuel: CNN's The Next List Profiles Jay Keasling ([https://www.youtube.com/watch?v=e7kC0knLaW8 Watch on YouTube])
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#Nova2011 [http://www.pbs.org/newshour/bb/science-jan-june11-nova_01-19/ Nova's ‘Making Stuff’ Explores Spinning of Steel-Strength Spider Silk (5 min)]
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// CNN Interview with Jay Keasling that mentions artemisinin and also focuses on biofuels.
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// Shows the largest piece of spider silk textile in the world and talks about 'spider goats'.
 
</biblio>
 
</biblio>
  
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#Dhami2013 pmid=24194735
 
#Dhami2013 pmid=24194735
 
// Self-healing concrete  
 
// Self-healing concrete  
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#Madison1999 pmid=10066830
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// Bioplastics
 
</biblio>
 
</biblio>

Latest revision as of 20:38, 22 March 2015

Silk fibers spun from recombinant protein expressed in 'E. coli' [1].

Download Pre-Discussion Questions (PDF)

The fibre spun with the native-sized recombinant spider silk protein showed similar mechanical properties to native spider silk, thus opening the possibility of its wide range of industrial and biomedical applications. [1].

Required Reading/Viewing

Error fetching PMID 20660779:
  1. Error fetching PMID 20660779: [Xia2010]
    Production of spider silk in E. coli.
  2. Nova's ‘Making Stuff’ Explores Spinning of Steel-Strength Spider Silk (5 min) [Nova2011]
    Shows the largest piece of spider silk textile in the world and talks about 'spider goats'.

Assigned Papers

Error fetching PMID 25240674:
Error fetching PMID 24194735:
Error fetching PMID 10066830:
  1. Error fetching PMID 25240674: [Zhong2014]
    Mussel adhesion proteins on 'E. coli'
  2. Error fetching PMID 24194735: [Dhami2013]
    Self-healing concrete
  3. Error fetching PMID 10066830: [Madison1999]
    Bioplastics
All Medline abstracts: PubMed | HubMed
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