Difference between revisions of "Recombinant DNA Technology (Biotechnology and Society)"

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(Required Reading)
(Discussion Questions)
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# Who imposed the 6-month moratorium on recombinant DNA research? Why?
 
# Who imposed the 6-month moratorium on recombinant DNA research? Why?
 
# What new dangers were possible with the use of recombinant DNA?
 
# What new dangers were possible with the use of recombinant DNA?
# Was the comparison of recombinant DNA to nuclear weapons appropriate at the time? Why? Why not? What about now?
+
# Was the comparison of recombinant DNA to nuclear weapons appropriate at the time? Why? Why not?
 
# How was the reaction of the public and government different from that of scientists?
 
# How was the reaction of the public and government different from that of scientists?
 +
# Which threats brought up by the scientist at Asilomar turned out to be unfounded? Which are we still concerned about today?
 
# What organizations or agencies oversee recombinant DNA research today?
 
# What organizations or agencies oversee recombinant DNA research today?
 
# What are the lasting effects of the Asilomar model for examining the safety of new biotechnology?
 
# What are the lasting effects of the Asilomar model for examining the safety of new biotechnology?

Revision as of 04:44, 3 September 2013

Required Reading

Figure from one of the first papers reporting the production of a recombinant DNA molecule [1].
Error fetching PMID 4342968:
  1. Error fetching PMID 4342968: [Jackson1972]
    Original paper reporting construction of first recombinant DNA molecule. You can skim the paper. The main result is shown in Fig. 1.
  2. Paul Berg. Asilomar and Recombinant DNA (Nobel Foundation) [Berg1980]
  3. ISBN:0309044863 [Fredrickson1991]
    Fredrickson, Donald S. "Asilomar and Recombinant DNA: The End of the Beginning" pages 258-307
    Read online at National Academies Press.
    Pages 259-264 are a brief history of molecular biology that can be skipped. Concentrate on pages 265-284.

Discussion Questions

  1. What experiments prompted the Asilomar conference? What new technologies had been developed that made them possible?
  2. Who imposed the 6-month moratorium on recombinant DNA research? Why?
  3. What new dangers were possible with the use of recombinant DNA?
  4. Was the comparison of recombinant DNA to nuclear weapons appropriate at the time? Why? Why not?
  5. How was the reaction of the public and government different from that of scientists?
  6. Which threats brought up by the scientist at Asilomar turned out to be unfounded? Which are we still concerned about today?
  7. What organizations or agencies oversee recombinant DNA research today?
  8. What are the lasting effects of the Asilomar model for examining the safety of new biotechnology?

Additional Background