Talk:CH391L/S14/MAGE

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Revision as of 12:56, 4 April 2014 by Aeg2338 (Talk | contribs)

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  • --Dennis Mishler (talk) 08:40, 1 April 2014 (CDT) Jordan, Files and figures aren't functioning properly. If you are unsure about how to fix this, look at the code for some of the other wiki pages. If you still have questions, let me know. We should make sure you know how to do this (not only for the class).
  • --Dennis Mishler (talk) 08:42, 1 April 2014 (CDT)Overall, a very nice page with a lot of useful information. I will leave it to others to critique the rest of the material.

--Chen-Hsun Tsai (talk) 02:00, 4 April 2014 (CDT) I think this wiki page is well written and has covered most of the content that people interested. But it seems like you have few paragraphs missed from the page? Like "Automation" and "De-extinction".

--Liz (talk) 07:05, 4 April 2014 (CDT)Very well-written. Figures, which I think would be really helpful, are still not coming through. I know I have less biology background than others in the class might, but I got a little lost when you explained the basics of the MAGE technique. This may be cleared up by one of your figures, but I didn't really follow how the insertion or deletion events actually occur in the oligo-mediated allelic replacement- a link to a wiki page/more info would suffice as well. Also noticing you have a Mulitplex typo in the top heading. For the lycopene pathway, I would move the first sentence/idea from DXP pathway into the little intro above- just get across the idea this is great MAGE target while defining lycopene, then get into the nitty-gritty below (personal preference). Same comments as Chen for Automation and De-extinction. For the citations, only references 1 and 4 are showing up, though I see at least 6 are cited in-article. The layout progresses through ideas very naturally. Only suggestion would be to get into the MAGE basic ideas a little more. Also, this method seems really elegant and efficient- how does this compare to other efforts to achieve the same goal? Some sentence (or more?) to put in in context might emphasize how great this is. Good job!

--Alejandro Gutierrez (talk) 07:56, 4 April 2014 (CDT) I agree with Liz that the layout flows very naturally. Aside from the comments above, I would mainly like to know about any other specific applications of MAGE. You mention other projects that the Church group have used it for; maybe just listing a few of those would be nice. I don't know exactly how much this technique has been used, but more examples would help give a feel for what sorts of projects MAGE would be useful for.