Talk:CH391L/S14/QuorumSensing
- --Dennis Mishler (talk) 16:34, 18 March 2014 (CDT) Great job, Mindy. A very good explanation/introduction to the topic. My one critique would be in the synthetic biology section. I would love to see a figure relating to one of the examples mentioned. I would also like to see another example of using Quorum sensing for some purpose, such as heading toward bacterial consortia.
- ----Jorge Vazquez (talk) 20:53, 20 March 2014 (CDT)Excellent job! Very little to improve. I would probably like to see an expanded section on the examples of quorum sensing in synthetic biology. Probably explained more in detail? But this is just my preference. I think the wiki is very well done.
--Dennis Mishler (talk) 14:05, 20 March 2014 (CDT) Gabo's critique
Overall Format and structure: I think you really laid out things really well. I liked that I could find links all throughout if I wanted more information on other concepts. I found paragraphs clear and concise.
Introduction and background material: Good intro and background material.
Methods and main body/concepts: When describing autoinducers, you mention that AI-2’s are used mainly in intraspecies communication. Is this any different than the use for AI-1’s or are AI-1’s also used mainly in intraspecies communication? If so, why not mention it for AI-1’s or simply say “also” for AI-2’s? Under the description for AI-1, since Luxl proteins do not directly synthesize HSL or AHL, I would clarify by saying “are responsible for the activation of synthesis of these lipids”, instead of saying that these are “responsible for synthesizing these”. I would take out “Both –” from the beginning of the sentence under AI-2, it makes it confusing and it’s redundant since you already mention it in that sentence. The next sentence can be improved by a slight change, exchanging the word “following” - the 2nd one - for “then” and it will flow better I guess. Also, is it really necessary to say “cell-specific”? Last sentence under Benefits of Quorum Sensing you mention bacterial-eukaryotic (interspecies) communication is important in pathogenic bacterial strains, but what the paper says is that communication is important for non-pathogenic interactions. In the case of pathogenic bacteria I think they rather say “signaling” is important. Relation to iGEM and future directions: Amazed by the pretty cool stuff iGEM teams have been doing with quorum sensing. I liked it very much and seems like there will be much more to come on this subject.
Figures, Figure legends, and citations: I think your report was well referenced and that images were good and helpful.
