Difference between revisions of "Wolbachia versus Gene Drives for Mosquito Control (Biotechnology and Society 2016)"
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Revision as of 14:26, 7 November 2016
Download Pre-Discussion Questions (MS Word)
Download Policy Czar Template (MS Word)
Everyone: Overview
Required Reading/Viewing
- https://www.sciencenews.org/article/gene-drives-spread-their-wings?mode=pick&context=170
- https://www.youtube.com/watch?v=rD8SmacBUcU
- Mosquito Is Next Weapon to Fight Malaria Caroline ChenBloomberg News June 16, 2016.
- https://www.youtube.com/watch?v=5V9gbgICPKY
- http://nas-sites.org/gene-drives/
Additional Resources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1691325/
- Regulating gene drives https://www.ncbi.nlm.nih.gov/pubmed/25035410
- Concerning RNA-guided gene drives for the alteration of wild populations. https://www.ncbi.nlm.nih.gov/pubmed/?term=25035423
Wolbachia Czar
Required Reading/Viewing
- http://www.nature.com/news/us-reviews-plan-to-infect-mosquitoes-with-bacteria-to-stop-disease-1.19967
- https://www.wired.com/2016/08/california-city-fending-off-zika-releasing-40000-mosquitoes-every-week/
- https://www.scientificamerican.com/article/how-a-tiny-bacterium-called-wolbachia-could-defeat-dengue/
- http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0002688
Medea Gene Drive Czar
- Akbari, OS., et al. (2014) Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. ACS Synthetic Biology 3:915–928.
- Akbari OS, et al. (2013) A synthetic gene drive system for local, reversible modification and suppression of insect populations. Curr Biol. 23:671-677.
- Wimmer EA. (2013) Comment: Insect biotechnology: controllable replacement of disease vectors. Curr Biol. 23:R453-R456.
Additional Resources
- Champer J, Buchman A, Akbari OS. (2016) Cheating evolution: engineering gene drives to manipulate the fate of wild populations. Nat. Rev. Genet. 17:146–159.
