Difference between revisions of "Wolbachia versus Gene Drives for Mosquito Control (Biotechnology and Society 2016)"
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* Champer J, Buchman A, Akbari OS. (2016) [https://www.ncbi.nlm.nih.gov/pubmed/26875679 Cheating evolution: engineering gene drives to manipulate the fate of wild populations]. ''Nat. Rev. Genet.'' '''17''':146–159. | * Champer J, Buchman A, Akbari OS. (2016) [https://www.ncbi.nlm.nih.gov/pubmed/26875679 Cheating evolution: engineering gene drives to manipulate the fate of wild populations]. ''Nat. Rev. Genet.'' '''17''':146–159. | ||
| − | == Ethics | + | == Gene Drive Ethics Czar == |
==== Required Reading/Viewing ==== | ==== Required Reading/Viewing ==== | ||
* Oye K.A., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/25035410 Biotechnology. Regulating gene drives.] ''Science'' '''345''':626–628. | * Oye K.A., et al. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/25035410 Biotechnology. Regulating gene drives.] ''Science'' '''345''':626–628. | ||
* Esvelt K.M., et al. [https://www.ncbi.nlm.nih.gov/pubmed/25035423 Concerning RNA-guided gene drives for the alteration of wild populations]. '''Elife''' ''3'':e03401. | * Esvelt K.M., et al. [https://www.ncbi.nlm.nih.gov/pubmed/25035423 Concerning RNA-guided gene drives for the alteration of wild populations]. '''Elife''' ''3'':e03401. | ||
Revision as of 15:45, 7 November 2016
Download Pre-Discussion Questions (MS Word)
Download Policy Czar Template (MS Word)
Everyone: Overview
Required Reading/Viewing
- How Mosquitoes Use Six Needles to Suck Your Blood Deep Look via YouTube. Jun 7, 2016.
- Video of Bill Gates Releasing Mosquitoes Into Audience TED Talk excerpt on YouTube. Jul 8, 2009.
- Mosquito Is Next Weapon to Fight Malaria Caroline Chen Bloomberg News June 16, 2016.
Watch the 4 minute video at the top of the page. - Gene drives spread their wings Tina Saey Science News Dec 2, 1025.
- Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty, and Aligning Research with Public Values The National Academy of Sciences Report
Look at the "4 Page report in Brief".
Additional Resources
- Burt A. (2003) Site-specific selfish genes as tools for the control and genetic engineering of natural populations. Proc. Biol. Sci. 270:921–928.
Early paper discussing general concept and issues of gene drives.
Wolbachia Czar
Required Reading/Viewing
- http://www.nature.com/news/us-reviews-plan-to-infect-mosquitoes-with-bacteria-to-stop-disease-1.19967
- https://www.wired.com/2016/08/california-city-fending-off-zika-releasing-40000-mosquitoes-every-week/
- https://www.scientificamerican.com/article/how-a-tiny-bacterium-called-wolbachia-could-defeat-dengue/
- http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0002688
Medea Gene Drive Czar
- Akbari, OS., et al. (2014) Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. ACS Synthetic Biology 3:915–928.
- Akbari OS, et al. (2013) A synthetic gene drive system for local, reversible modification and suppression of insect populations. Curr Biol. 23:671-677.
- Wimmer EA. (2013) Comment: Insect biotechnology: controllable replacement of disease vectors. Curr Biol. 23:R453-R456.
Additional Resources
- Champer J, Buchman A, Akbari OS. (2016) Cheating evolution: engineering gene drives to manipulate the fate of wild populations. Nat. Rev. Genet. 17:146–159.
Gene Drive Ethics Czar
Required Reading/Viewing
- Oye K.A., et al. (2014) Biotechnology. Regulating gene drives. Science 345:626–628.
- Esvelt K.M., et al. Concerning RNA-guided gene drives for the alteration of wild populations. Elife 3:e03401.
