Difference between revisions of "Analog Genetic Circuits (Microbes as Machines)"
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− | + | [[File:repressilator_plasmids.png|400px|thumb|right|Repressilator <cite>Gibson2010</cite>. Image from [http://en.wikipedia.org/wiki/Repressilator Wikipedia article].]] | |
− | [[ | + | ==== [[Media:Spring2015_Analog_Genetic_Circuits_Pre-Discussion_Questions.pdf|Download Pre-Discussion Questions (PDF)]] ==== |
<blockquote> | <blockquote> | ||
− | <font size="4"> | + | <font size="4">Such 'rational network design' may lead both to the engineering of new cellular behaviours and to an improved understanding of naturally occurring networks <cite>Elowitz2000</cite>.</font> |
</blockquote> | </blockquote> | ||
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<biblio> | <biblio> | ||
#Elowitz2000 pmid=10659856 | #Elowitz2000 pmid=10659856 | ||
− | // Describes the artificial "repressilator" circuit. | + | // Describes the artificial "repressilator" circuit. Also, view the [http://www.elowitz.caltech.edu/publications/brepressilator-01-bwfluor.avi movie] of it in action. |
− | #Anderson2014 | + | #Gardner2000 pmid=10659857 |
+ | // Describes an artificial "toggle switch" circuit. | ||
+ | #Anderson2014 Explanation of the toggle switch and repressilator by J. Chris Anderson ([https://www.youtube.com/watch?v=0ksvU6Bckbk YouTube]) | ||
</biblio> | </biblio> | ||
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<biblio> | <biblio> | ||
+ | #Friedland2009 pmid=19478183 | ||
+ | // Bacteria that can count to three. | ||
#Prindle2012 pmid=22178928 | #Prindle2012 pmid=22178928 | ||
// Synchronization and modulation of oscillations across multiple cell populations. | // Synchronization and modulation of oscillations across multiple cell populations. | ||
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<biblio> | <biblio> | ||
− | #Chandran2011 Repressilator in TinkerCell([https://www.youtube.com/watch?v=23NTnICU0qw YouTube]) | + | #Chandran2011 Repressilator in TinkerCell ([https://www.youtube.com/watch?v=23NTnICU0qw YouTube]) |
− | // Movie shows how to create and model the repressilator in TinkerCell | + | // Movie shows how to create and model the repressilator in [http://www.tinkercell.com TinkerCell] |
</biblio> | </biblio> |
Latest revision as of 21:35, 16 February 2015
Contents |
Download Pre-Discussion Questions (PDF)
Such 'rational network design' may lead both to the engineering of new cellular behaviours and to an improved understanding of naturally occurring networks [2].
Required Reading/Viewing
Error fetching PMID 10659856:
Error fetching PMID 10659857:
Error fetching PMID 10659857:
- Error fetching PMID 10659856:
Describes the artificial "repressilator" circuit. Also, view the movie of it in action. - Error fetching PMID 10659857:
Describes an artificial "toggle switch" circuit. - Explanation of the toggle switch and repressilator by J. Chris Anderson (YouTube)
Assigned Papers
Error fetching PMID 19478183:
Error fetching PMID 22178928:
Error fetching PMID 22178928:
- Error fetching PMID 19478183:
Bacteria that can count to three. - Error fetching PMID 22178928:
Synchronization and modulation of oscillations across multiple cell populations.
Additional Resources
- Repressilator in TinkerCell (YouTube)
Movie shows how to create and model the repressilator in TinkerCell