Difference between revisions of "Chemical Synthesis of Life (Biotechnology and Society 2016)"
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| − | ==== [[Media:Chemical_Synthesis_of_Life_Pre- | + | __NOTOC__ |
| + | [[File:Szostak-Vesicle.jpg|380px|thumb|right|Protocell consisting of a fatty acid vesicle encapsulating nucleic acids. From [http://exploringOrigins.org ExploringOrigins.org]. ]] | ||
| + | ==== [[Media:Chemical_Synthesis_of_Life_Pre-Discussion_Questions_2016F.docx| Download Pre-Discussion Questions (MS Word)]] ==== | ||
| + | ==== [[Media:Policy_Czar_Template.docx | Download Policy Czar Template (MS Word)]] ==== | ||
| − | + | == Everyone: Two Types of Protocells == | |
== Required Reading/Viewing == | == Required Reading/Viewing == | ||
We'll discuss two different types of chemically synthesized "protocells". | We'll discuss two different types of chemically synthesized "protocells". | ||
| − | + | * [http://www.ted.com/talks/martin_hanczyc_the_line_between_life_and_not_life.html The line between life and not-life] Martin Hanczyc ''TED Talk'' May 2011. (15 min). | |
| − | + | * [http://exploringorigins.org/protocell.html Exploring Life's Origins website] Read the three main pages linked by the titles Nucleic Acids, Fatty Acids, and Protocells to learn about the Szostak protocell model. Watch the short embedded movies. | |
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| − | == Additional Reading/Viewing == | + | ==== Additional Resources ==== |
| − | + | * [http://www.exploringorigins.org/ Exploring Life's Origins Main Website] – includes several other interesting sections on prebiotic chemistry and the RNA World. | |
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| − | + | == Hanczyc Protocell Czar == | |
| + | |||
| + | ==== Required Reading/Viewing ==== | ||
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| + | * Toyota, T., et al. (2009) [https://www.ncbi.nlm.nih.gov/pubmed/19351200 Self-propelled oil droplets consuming "fuel" surfactant.] ''J Am Chem Soc'' '''131''':5012-5013. Paper describing the chemistry behind the movies shown in the TED Talk. | ||
| + | * Hanczyc M.M. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/25525912 Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow.] ''Life'' '''4''':1038–1049. | ||
| + | * Lagzi I., et al. (2010) [https://www.ncbi.nlm.nih.gov/pubmed/20063877 Maze solving by chemotactic droplets.] ''J Am Chem Soc'' '''132''':1198–1199. | ||
| + | |||
| + | ==== Additional Resources ==== | ||
| + | * [http://pubs.acs.org/doi/suppl/10.1021/ja9076793 Maze solving by chemotactic droplets movies] | ||
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| + | == Szostak Protocells Czar == | ||
| + | |||
| + | ==== Required Reading/Viewing ==== | ||
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| + | * [http://science.sciencemag.org/content/342/6162/1032.full The Life Force] Robert F. Service ''Science'' Nov 2013. Interview with Szostak explaining experiments. | ||
| + | * [http://www.ibiology.org/ibioseminars/evolution-ecology/jack-szostak-part-1.html Part 1: The Origin of Cellular Life on Earth] Jack Szostak ''iBiology Lecture'' July 2011 (55 minutes). You can skip past the general intro to minute 10 with the slide "Modern Life". | ||
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| + | ==== Additional Resources ==== | ||
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| + | * Blain, J.C., Szostak, J.W. (2014) [https://www.ncbi.nlm.nih.gov/pubmed/24606140 Progress toward synthetic cells.] ''Annu Rev Biochem'' '''83''':615–640. Provides a very complete account of this research. | ||
Latest revision as of 14:45, 28 November 2016
Download Pre-Discussion Questions (MS Word)
Download Policy Czar Template (MS Word)
Everyone: Two Types of Protocells
Required Reading/Viewing
We'll discuss two different types of chemically synthesized "protocells".
- The line between life and not-life Martin Hanczyc TED Talk May 2011. (15 min).
- Exploring Life's Origins website Read the three main pages linked by the titles Nucleic Acids, Fatty Acids, and Protocells to learn about the Szostak protocell model. Watch the short embedded movies.
Additional Resources
- Exploring Life's Origins Main Website – includes several other interesting sections on prebiotic chemistry and the RNA World.
Hanczyc Protocell Czar
Required Reading/Viewing
- Toyota, T., et al. (2009) Self-propelled oil droplets consuming "fuel" surfactant. J Am Chem Soc 131:5012-5013. Paper describing the chemistry behind the movies shown in the TED Talk.
- Hanczyc M.M. (2014) Droplets: Unconventional Protocell Model with Life-Like Dynamics and Room to Grow. Life 4:1038–1049.
- Lagzi I., et al. (2010) Maze solving by chemotactic droplets. J Am Chem Soc 132:1198–1199.
Additional Resources
Szostak Protocells Czar
Required Reading/Viewing
- The Life Force Robert F. Service Science Nov 2013. Interview with Szostak explaining experiments.
- Part 1: The Origin of Cellular Life on Earth Jack Szostak iBiology Lecture July 2011 (55 minutes). You can skip past the general intro to minute 10 with the slide "Modern Life".
Additional Resources
- Blain, J.C., Szostak, J.W. (2014) Progress toward synthetic cells. Annu Rev Biochem 83:615–640. Provides a very complete account of this research.
