Cloning versus Stem Cell Therapies (Biotechnology and Society 2016)
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Everyone: Dolly the Sheep and Pet Cloning
Required Reading/Viewing
- Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH (1997) Viable offspring derived from fetal and adult mammalian cells. Nature 385:810–813.
Paper describing cloning of Dolly the sheep. - Stewart C (1997) Nuclear transplantation. An udder way of making lambs. Nature 385:769, 771.
News and Views article accompanying Dolly article. - Pera M, Trounson A (2013) Cloning debate: Stem-cell researchers must stay engaged. Nature 498:159–161.
Compares the development of ESC, SCNT, and iPSC technologies and mentions some applications. - My Friend Again: Pet Cloning Service
See especially, the "My Dog has died" link.
Additional Resources
- The Dark Side of Pet Cloning Emily Singer MIT Technology Review. January 30, 2009.
Comment about pet cloning services. - This American Life piece on (Second) Chance the cloned Bull
- How Cloning Works
Woo Suk Hwang Czar
Required Reading/Viewing
- Cyranoski D (2014) Cloning comeback. Nature 505:468–471.
Story of the career of Woo Suk Hwang. - Hwang WS et al. (2005) Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science 308:1777–1783.
Second retracted paper. - Be sure to describe specifically what the scientific misconduct was for the two major studies and what the penalties were.
Parkinson's Czar
Required Reading/Viewing
- http://content.iospress.com/articles/journal-of-parkinsons-disease/jpd160798
- https://clinicaltrials.gov/ct2/results?term=stem+cells+AND+parkinson%27s